Chondroitin Sulfate Clinical Study

Kuznetsov AS, Khovratovich VI, Ioffe DV, Popov AV.

Heparin, chodroitin sulfates A, B, C, clofibrate and its derivatives as well as diphenyl disulfonate substituted the fluorescent probe I-aniline naphthalene-8-sulfonate in blood plasma low density lipoproteins. Constants of association for complexes of low density lipoproteins-heparin and chondroitin sulfate C, calculated on the basis of these data, were equal to 1.15.10(6) and 0,46.10(6) M-1, respectively. At the some time, the ligands studied altered the lipoprotein charges.

PMID: 6414179 [PubMed - indexed for MEDLINE]

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